Organic disulfides
Sigma Aldrich Fine Chemicals Biosciences Dimethyl disulfide natural250G
Dimethyl disulfide natural250G
Medchemexpress LLC 2,6-Dichlorodiphenylamine | 15307-93-4 | 99.8% | 238.12 | 1 ML
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and demonstrates anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, functioning as a COX inhibitor with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, respectively. This product is intended for research use only and is not sold to patients.
- Analogue of diclofenac sodium
- Demonstrates anti-Candida albicans activity
- Potent and nonselective anti-inflammatory agent
- Functions as a COX inhibitor
- High purity of 99.78%
- Causes skin irritation
- Causes serious eye irritation
- Very toxic to aquatic life with long lasting effects
- Store at 4°C, protected from light
- Avoid inhalation, contact with eyes and skin
- Avoid dust and aerosol formation
- Use in areas with appropriate exhaust ventilation
Sigma Aldrich Fine Chemicals Biosciences Dimethyl disulfide natural50G
Dimethyl disulfide natural50G
Medchemexpress LLC Captopril disulfide | 64806-05-9 | MFCD08063643 | 99.3% | 432.55 | C18H28N2O6S2 | 100MG
Captopril disulfide is the disulfide metabolite of the ACE inhibitor captopril with reported antihypertensive activity. It is supplied as an analytical standard and research reagent for analytical, pharmacological, and method development applications.
- Analytical standard for research and analytical applications.
- Disulfide metabolite of captopril with antihypertensive activity.
- High purity (99.29%).
- Molecular formula C18H28N2O6S2.
- Molecular weight 432.55 g/mol.
- Available in multiple sizes, including 100 mg.
- Suitable for use as a reference material in method development and quality control.
Cambridge Isotope Laboratories Dicyclohexyl phthalate (unlabeled) 100 ug/mL in nonane 1 2 mL
Dicyclohexyl phthalate (unlabeled) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC Dibenzyl disulfide | 150-60-7 | MFCD00004783 | 99.9% | 246.39 | 500 G
Dibenzyl disulfide is an endogenous metabolite. It is a solid with a white to off-white appearance.
- Purity: 99.94%
- Molecular Weight: 246.39
- CAS number: 150-60-7
- Formula: C14H14S2
- Initial source: Plants Petiveriaceae Petiveria alliacea
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; In solvent at -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC (R)-Zelebrudomide ((R)-NX-2127) | 3024312-52-2 | C39H45N9O5 | 50 MG
(R)-Zelebrudomide ((R)-NX-2127), also known as (R)-Compound 28, is an isomer of the BTK PROTAC degrader Zelebrudomide. It is intended for research use only.
- Molecular weight: 719.83
- Chemical formula: C39H45N9O5
- Appearance: Solid
- Color: Light yellow to yellow
- Purity: 98.93%
- Shipping condition: Room temperature in continental US
- Storage condition: 4°C, protect from light
- Storage in solvent: -80°C for 6 months; -20°C for 1 month, protect from light
Medchemexpress LLC Zelebrudomide (NX-2127) | 2416131-46-7 | C39H45N9O5 | 100 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (BTK). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib. Zelebrudomide also catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with respective values of 25 nM and 54 nM. Additionally, it stimulates T cell activation and increases IL-2 production in primary human T Cells.
- Orally active PROTAC degrader targets Bruton's Tyrosine Kinase (BTK).
- Inhibits proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib.
- Catalyzes degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with respective values of 25 nM and 54 nM.
- Stimulates T cell activation and increases IL-2 production in primary human T Cells.
- Demonstrates potent degradation of BTK in vivo.
- Results in superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice.
Medchemexpress LLC NX-2127 | 2416131-46-7 | C39H45N9O5 | 200 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader targeting Bruton's Tyrosine Kinase (Btk). It effectively inhibits proliferation of BTKC481S mutant TMD8 cells and catalyzes degradation of Ikaros (IKZF1) and Aiolos (IKZF3). It also stimulates T cell activation and increases IL-2 production.
- Orally active PROTAC degrader.
- Targets Bruton's tyrosine kinase (Btk).
- Inhibits BTKC481S mutant TMD8 cell proliferation (EC50 <30 nM).
- Catalyzes Ikaros (IKZF1) and Aiolos (IKZF3) degradation.
- Stimulates T cell activation; increases IL-2 production.
- Potent BTK degradation in cynomolgus monkeys in vivo.
- Superior tumor growth inhibition in WT TMD8 and C481S mutant xenograft models.
- Appearance: solid, light yellow to yellow.
- Purity: 99.72%.